Umbilical cord blood expansion with nicotinamide provides long-term multilineage engraftment
نویسندگان
چکیده
منابع مشابه
Umbilical cord blood expansion with nicotinamide provides long-term multilineage engraftment.
BACKGROUND Delayed hematopoietic recovery is a major drawback of umbilical cord blood (UCB) transplantation. Transplantation of ex vivo-expanded UCB shortens time to hematopoietic recovery, but long-term, robust engraftment by the expanded unit has yet to be demonstrated. We tested the hypothesis that a UCB-derived cell product consisting of stem cells expanded for 21 days in the presence of ni...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 2014
ISSN: 0021-9738
DOI: 10.1172/jci74556